Brk Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Brk Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | PTK6 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Breast Tumor Kinase. AA range:10-59 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP11570 |
Additional information
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The protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
PTK6, BRK, Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK
Human: Q13882, Mouse: Q64434
Human: 5753, Mouse: 20459