BMP-2 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | BMP-2 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | BMP2 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from Bone morphogenetic protein 2 at AA range: 341-390 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP11593 |
Additional information
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BMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of BMP2 causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
BMP2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A
Human: P12643, Mouse: P21274, Rat: P49001
Human: 650, Mouse: 12156, Rat: 29373