Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Guanine nucleotide exchange factor VAV3 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | VAV3 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173) |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12034 |
Additional information
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This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Guanine nucleotide exchange factor VAV3, VAV3, Guanine nucleotide exchange factor VAV3, VAV-3
Human: Q9UKW4, Mouse: Q9R0C8
Human: 10451, Mouse: 57257
