TNR8 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Tumor necrosis factor receptor superfamily member 8

Host

Rabbit

Isotype

IgG

Target protein

TNFRSF8

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP12070

Additional information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Tumor necrosis factor receptor superfamily member 8 ,CD30L receptor,Ki-1 antigen,Lymphocyte activation antigen CD30,CD antigen CD30
Human: P28908, Mouse: Q60846, Rat: P97525
Human: 943