Stat4 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Signal transducer and activator of transcription 4 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | STAT4 |
| Recommended applications | IF, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Synthesized peptide derived from human Stat4 around the non-phosphorylation site of Y693. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12145 |
Additional information
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The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Signal transducer and activator of transcription 4, STAT4, Signal transducer and activator of transcription 4
Human: Q14765, Mouse: P42228
Human: 6775