PCNT Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Pericentrin |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | PCNT |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12326 |
Additional information
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The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
Pericentrin ,Kendrin,Pericentrin-B
Human: O95613, Mouse: P48725
Human: 5116