NAIP Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Baculoviral IAP repeat-containing protein 1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | NAIP |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide from human protein at AA range: 1191-1240 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12430 |
Additional information
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This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Baculoviral IAP repeat-containing protein 1 ,Neuronal apoptosis inhibitory protein, Baculoviral IAP repeat-containing protein 1, Neuronal apoptosis inhibitory protein
Human: Q13075
Human: 4671, Mouse: 0