MARK1/2/3/4(Phospho Thr215) Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Serine/threonine-protein kinase MARK1/2/3/4

Host

Rabbit

Isotype

IgG

Target protein

MARK1/2/3/4

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4 around the phosphorylation site of Thr215. AA range:181-230

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP12508

Additional information

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,May play a role in cytoskeletal stability.,Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,Contains 1 KA1 (kinase-associated) domain.,Contains 1 protein kinase domain.,Contains 1 UBA domain.,subcellular location:Appears to localize to an intracellular network.,tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,
Serine/threonine-protein kinase MARK1/2/3/4, MARK1, KIAA1477, MARK, Serine/threonine-protein kinase MARK1, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c, Par-1c, Par1c, MARK2, EMK1, Serine/threonine-protein kinase MARK2, ELKL motif kinase 1, EMK-1, MAP/microtubule affin
Human: Q9P0L2/Q7KZI7/P27448/Q96L34, Rat: O08678/O08679/Q8VHF0
Human: 4139/2011/4140/57787, Mouse: 226778/13728/17169/232944, Rat: 117016/60328/170577