Kv1.1 potassium channel Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Potassium voltage-gated channel subfamily A member 1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | KCNA1 |
| Recommended applications | IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic Peptide of Kv1.1 potassium channel |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12547 |
Additional information
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This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Potassium voltage-gated channel subfamily A member 1 ,Voltage-gated K,+ channel HuKI,Voltage-gated potassium channel HBK1,Voltage-gated potassium channel subunit Kv1.1, KCNA1, Potassium voltage-gated channel subfamily A member 1, Voltage-gated K,+ channel HuKI, Voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv1.1
Human: Q09470, Mouse: P16388, Rat: P10499
Human: 3736