KCNN3 (SK3) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Small conductance calcium-activated potassium channel protein 3 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | KCNN3 |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Rat |
| Immunogen | Synthetic Peptide of KCNN3 (SK3) |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12560 |
Additional information
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Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript v
Small conductance calcium-activated potassium channel protein 3 ,SK3,SKCa 3,SKCa3,KCa2.3, Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3
Human: Q9UGI6, Mouse: P58391, Rat: P70605
Human: 3782