HUWE1 Polyclonal Antibody
Prices are excluding VAT and shipping costs
Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | E3 ubiquitin-protein ligase HUWE1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | HUWE1 |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12646 |
Additional information
Prev
Next
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
E3 ubiquitin-protein ligase HUWE1 ,EC 6.3.2.-,ARF-binding protein 1,ARF-BP1,HECT, UBA and WWE domain-containing protein 1,Homologous to E6AP carboxyl terminus homologous protein 9,HectH9,L
Human: Q7Z6Z7, Mouse: Q7TMY8, Rat: P51593
Human: 10075