Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Granzyme B |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | GZMB |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from human Granzyme B Polyclonal |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12721 |
Additional information
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This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
Granzyme B ,EC 3.4.21.79,C11,CTLA-1,Cathepsin G-like 1,CTSGL1,Cytotoxic T-lymphocyte proteinase 2,Lymphocyte protease,Fragmentin-2,Granzyme-2,Human lymphocyte protein,HLP,SECT,, Granzyme B, EC 3.4.21.79, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E
Human: P10144, Mouse: P04187, Rat: P18291
Human: 3002, Mouse: 14939, Rat: 100361468
