Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Deleted in malignant brain tumors 1 protein |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | DMBT1 |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12862 |
Additional information
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Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Deleted in malignant brain tumors 1 protein ,Glycoprotein 340,Gp-340,Hensin,Salivary agglutinin,SAG,Surfactant pulmonary-associated D-binding protein
Human: Q9UGM3, Mouse: Q60997, Rat: Q8CIZ5
Human: 1755
