CD314 Polyclonal Antibody

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CD314 Polyclonal Antibody
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Product information

Price

€175, €275, €395
Size

20 µl/µg | 50 µl/µg | 100 µl/µg
Short name

NKG2-D type II integral membrane protein
Host

Rabbit
Isotype

IgG
Target protein

KLRK1
Recommended applications

ELISA, IF, IHC-p
Reactivity

Human, Mouse, Rat
Immunogen

Synthetic peptide from human protein at AA range: 167-216
Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.
Storage

-20°C for 1 year
Product code

MB-AP12976

Additional information

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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of
NKG2-D type II integral membrane protein ,Killer cell lectin-like receptor subfamily K member 1,NK cell receptor D,NKG2-D-activating NK receptor,CD antigen CD314, NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD antigen CD314
Human: P26718, Mouse: O54709
Human: 100528032, Mouse: 27007