CASR Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Extracellular calcium-sensing receptor |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CASR |
| Recommended applications | IF, IHC-p, WB |
| Reactivity | Mouse, Rat |
| Immunogen | Synthetic Peptide of CASR |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13018 |
Additional information
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The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Extracellular calcium-sensing receptor, CASR, GPRC2A, PCAR1, Extracellular calcium-sensing receptor, CaSR, Parathyroid cell calcium-sensing receptor, PCaR1
Human: P41180, Mouse: Q9QY96, Rat: P48442
Human: 846