CAC1A Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Voltage-dependent P/Q-type calcium channel subunit alpha-1A |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CACNA1A |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1401-1450 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13032 |
Additional information
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Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits
Voltage-dependent P/Q-type calcium channel subunit alpha-1A ,Brain calcium channel I,BI,Calcium channel, L type, alpha-1 polypeptide isoform 4,Voltage-gated calcium channel subunit alpha Cav2.1
Human: O00555, Mouse: P97445, Rat: P54282
Human: 773