Trk C(Phospho Tyr516) Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

NT-3 growth factor receptor

Host

Rabbit

Isotype

IgG

Target protein

NTRK3

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Trk C around the phosphorylation site of Tyr516. AA range:482-531

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP13295

Additional information

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that| upon neurotrophin binding| phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas| secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
NT-3 growth factor receptor, NTRK3, TRKC, NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase
Human: Q16288, Mouse: Q6VNS1, Rat: Q03351
Human: 4916, Mouse: 18213, Rat: 29613