TGF beta 1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Transforming growth factor beta-1

Host

Rabbit

Isotype

IgG

Target protein

TGFB1

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta1. AA range:336-385

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP13299

Additional information

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation| differentiation and growth| and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i
Transforming growth factor beta-1, TGFB1, TGFB, Transforming growth factor beta-1, TGF-beta-1
Human: P01137, Mouse: P04202, Rat: P17246
Human: 7040, Mouse: 21803, Rat: 59086