TGFBeta3 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | TGFbeta3 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | TGFB3 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TGF beta3. AA range:261-310 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP13981 |
Additional information
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TGFB3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Transforming growth factor beta-3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia.
TGFB3, Transforming growth factor beta-3, TGF-beta-3
Human: P10600, Mouse: P17125, Rat: Q07258
Human: 7043, Rat: 25717