Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Socius Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | UBXN11 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBXD5. AA range:131-180 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14166 |
Additional information
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UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1. and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for UBXN11.
UBXN11, SOC, UBXD5, PP2243, UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5
Human: Q5T124, Mouse: Q9D572
Human: 91544
