Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Rho GDIalpha Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | ARHGDIA |
| Recommended applications | ELISA, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGDIA. AA range:140-189 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14353 |
Additional information
Prev
Next
ARHGDIA encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.
ARHGDIA, GDIA1, Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI alpha
Human: P52565, Mouse: Q99PT1, Rat: Q5XI73
Human: 396, Mouse: 192662, Rat: 360678
