Rag A/B Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Rag A/B Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | RRAGA |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14411 |
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Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14. K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
RRAGA, Ras-related GTP-binding protein A, Rag A, RagA, Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1, RRAGB, Ras-related GTP-binding protein B, Rag B, RagB
Human: Q7L523/Q5VZM2, Rat: Q63486/Q63487
Human: 10670/10325, Mouse: 68441/245670, Rat: 117044/100909655