PU.1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

PU.1 Antibody

Host

Rabbit

Isotype

IgG

Target protein

SPI1

Reactivity

Human, Monkey, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human SPI1. AA range:181-230

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP14465

Additional information

SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. Spi-1 proto-oncogene can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this SPI1.
SPI1, Transcription factor PU.1, 31 kDa-transforming protein
Human: P17947, Mouse: P17433, Rat: Q6BDS1
Human: 6688, Mouse: 20375, Rat: 366126