Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Per2 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | PER2 |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human, Mouse |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Period Circadian Protein 2. AA range:636-685 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP14655 |
Additional information
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PER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER2 may increase the risk of getting certain cancers and have been linked to sleep disorders.
PER2, KIAA0347, Period circadian protein homolog 2, hPER2, Circadian clock protein PERIOD 2
Human: O15055, Mouse: O54943
Human: 8864, Mouse: 18627
