MyD88 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | MyD88 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | MYD88 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP15031 |
Additional information
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MyD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
MYD88, Myeloid differentiation primary response protein MyD88
Human: Q99836, Mouse: P22366, Rat: Q6Y1S1
Human: 4615, Mouse: 17874, Rat: 301059