ABCG2 Monoclonal Antibody

Categories: ,

Prices are excluding VAT and shipping costs

Product information

Price

€240, €410

Size

50 µl/µg | 100 µl/µg

Short name

ATP-binding cassette sub-family G member 2

Host

Mouse

Isotype

IgG

Target protein

ABCG2

Reactivity

Human, Monkey, Mouse

Immunogen

Purified recombinant fragment of human ABCG2 expressed in E. Coli.

Purification

Affinity purification

Formulation

Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10481

Additional information

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
ABCG2, ABCP, BCRP, BCRP1, MXR, ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, CD antigen CD338
Human: Q9UNQ0, Mouse: Q7TMS5
Human: 9429, Mouse: 26357