AMPK alpha 1/2(Phospho Thr183/172) Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | PRKAA1 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | AAPK1 |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Pig, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12003 |
Additional information
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The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
PRKAA1| PRKAA1| AMPK1| 5'-AMP-activated protein kinase catalytic subunit alpha-1| AMPK subunit alpha-1| Acetyl-CoA carboxylase kinase| ACACA kinase| Hydroxymethylglutaryl-CoA reductase kinase| HMGCR kinase| Tau-protein kinase PRKAA1| PRKAA2| AMPK|
Human: Q13131/P54646, Rat: P54645/Q09137
Human: 5562/5563, Mouse: 105787/108079, Rat: 65248/78975