AMPK Alpha1 Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | 5'-AMP-activated protein kinase catalytic subunit alpha-1 |
| Host | Mouse |
| Isotype | IgG |
| Target protein | AAPK1 |
| Recommended applications | ELISA, FCM, ICC, IF, IHC-p, WB |
| Reactivity | Human, Monkey, Mouse, Rat |
| Immunogen | Purified recombinant fragment of human AMPKα1 expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10470 |
Additional information
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The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
PRKAA1, AMPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase
Human: Q13131, Mouse: Q5EG47, Rat: P54645
Human: 5562, Mouse: 105787, Rat: 65248