Ang-1 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Ang-1 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | ANGPT1 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANGPT1. AA range:1-50 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP11812 |
Additional information
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ANGPT1 encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin-1 encoded by ANGPT1 is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
ANGPT1, KIAA0003, Angiopoietin-1, ANG-1
Human: Q15389, Mouse: O08538, Rat: O35460
Human: 284, Rat: 89807