ApoE Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | Apolipoprotein E |
| Host | Mouse |
| Isotype | IgG |
| Target protein | APOE |
| Recommended applications | ELISA, FCM, IF, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Purified recombinant fragment of human ApoE expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10464 |
Additional information
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The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
APOE, Apolipoprotein E, Apo-E
Human: P02649, Mouse: P08226
Human: 348