ATP7A Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | ATP7A Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | ATP7A |
| Recommended applications | ELISA, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP7A. AA range:591-640 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP11666 |
Additional information
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ATP7A (ATPase copper transporting alpha) encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in ATP7A are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
ATP7A, MC1, MNK, Copper-transporting ATPase 1, Copper pump 1, Menkes disease-associated protein
Human: Q04656, Mouse: Q64430, Rat: P70705
Human: 538, Mouse: 11977, Rat: 24941