Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | BH3-interacting domain death agonist |
Host | Mouse |
Isotype | IgG |
Target protein | BID |
Recommended applications | ELISA, FCM, ICC, IF, IHC-p, WB |
Reactivity | Human |
Immunogen | Purified recombinant fragment of human BID expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10441 |
Additional information
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)| CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
BID, BH3-interacting domain death agonist, p22 BID, BID
Human: P55957, Mouse: P70444
Human: 637