Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | Tyrosine-protein kinase BTK |
Host | Mouse |
Isotype | IgG |
Target protein | BTK |
Recommended applications | ELISA, ICC, IF, IHC-p, WB |
Reactivity | Human, Monkey |
Immunogen | Purified recombinant fragment of Btk expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10427 |
Additional information
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
BTK, AGMX1, ATK, BPK, Tyrosine-protein kinase BTK, Agammaglobulinaemia tyrosine kinase, ATK, B-cell progenitor kinase, BPK, Bruton tyrosine kinase
Human: Q06187, Mouse: P35991
Human: 695