c-Rel Monoclonal Antibody
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Product information
| Price | €240, €410 |
|---|---|
| Size | 50 µl/µg | 100 µl/µg |
| Short name | Proto-oncogene c-Rel |
| Host | Mouse |
| Isotype | IgG |
| Target protein | REL |
| Recommended applications | ELISA, ICC, IF, IHC-p, WB |
| Reactivity | Human, Mouse |
| Immunogen | Purified recombinant fragment of human c-Rel expressed in E. Coli. |
| Purification | Affinity purification |
| Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
| Storage | -20°C for 1 year |
| Product code | MB-AM10422 |
Additional information
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This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
REL, Proto-oncogene c-Rel
Human: Q04864, Mouse: P15307
Human: 5966