Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | CBX2 Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | CBX2 |
Recommended applications | ELISA, IHC-p |
Reactivity | Human, Mouse |
Immunogen | Synthesized peptide derived from the N-terminal region of human CBX2. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP11431 |
Additional information
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CBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male-to-female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for CBX2.
CBX2, Chromobox protein homolog 2
Human: Q14781, Mouse: P30658
Human: 84733, Mouse: 12416