Product information
Price | €240, €410 |
---|---|
Size | 50 µl/µg | 100 µl/µg |
Short name | Cell division protein kinase 5 |
Host | Mouse |
Isotype | IgG |
Target protein | CDK5 |
Recommended applications | ELISA, FCM, ICC, IF, IHC-p, WB |
Reactivity | Human, Monkey, Rat |
Immunogen | Purified recombinant fragment of human Cdk5 expressed in E. Coli. |
Purification | Affinity purification |
Formulation | Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol. |
Storage | -20°C for 1 year |
Product code | MB-AM10370 |
Additional information
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This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.
CDK5, CDKN5, Cyclin-dependent kinase 5, Cell division protein kinase 5, Serine, threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit
Human: Q00535, Mouse: P49615, Rat: Q03114
Human: 1020140908