Product information
Price | €175, €275, €395 |
---|---|
Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | CEP170 Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | CEP170 |
Recommended applications | ELISA, IHC-p, WB |
Reactivity | Human |
Immunogen | The antiserum was produced against synthesized peptide derived from human CEP170. AA range:701-750 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP11281 |
Additional information
Prev
Next
The product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.
CEP170, FAM68A, KAB, KIAA0470, Centrosomal protein of 170 kDa, Cep170, KARP-1-binding protein, KARP1-binding protein
Human: Q5SW79, Mouse: Q6A065
Human: 9859