CHD8 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Chromodomain-helicase-DNA-binding protein 8 |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CHD8 |
| Recommended applications | IF, IHC-p |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP12943 |
Additional information
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This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Chromodomain-helicase-DNA-binding protein 8 ,CHD-8,EC 3.6.4.12,ATP-dependent helicase CHD8,Helicase with SNF2 domain 1
Human: Q9HCK8, Mouse: Q09XV5, Rat: Q9JIX5
Human: 57680