Che-1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Che-1 Antibody

Host

Rabbit

Isotype

IgG

Target protein

AATF

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human AATF. AA range:10-59

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP11250

Additional information

Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.
AATF, CHE1, DED, HSPC277, Protein AATF, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1
Human: Q9NY61, Mouse: Q9JKX4, Rat: Q9QYW0
Human: 26574, Mouse: 56321, Rat: 114512