Product information
Price | €175, €275, €395 |
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Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | Che-1 Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | AATF |
Recommended applications | ELISA, IHC-p, WB |
Reactivity | Human, Mouse, Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human AATF. AA range:10-59 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP11250 |
Additional information
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Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.
AATF, CHE1, DED, HSPC277, Protein AATF, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1
Human: Q9NY61, Mouse: Q9JKX4, Rat: Q9QYW0
Human: 26574, Mouse: 56321, Rat: 114512