Cleaved PARP Monoclonal Antibody(Mix)

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Poly (ADP-ribose) polymerase 1

Host

Mouse

Isotype

IgG

Target protein

PARP1

Reactivity

Human

Immunogen

Synthetic Peptide of Cleaved PARP

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Formulation

PBS; pH 7.4; containing 0.5%BSA; 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10540

Additional information

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1
Human: P09874, Mouse: P11103, Rat: P27008
Human: 14225591