Connexin 43 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Connexin 43 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | GJA1 |
| Recommended applications | ELISA, IF, IHC-p |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Connexin 43. AA range:226-275 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP11116 |
Additional information
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GJA1 is a member of the connexin gene family. Gap junction protein alpha 1 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Gap junction protein alpha 1 is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in GJA1 have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
GJA1, GJAL, Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein
Human: P17302, Mouse: P23242, Rat: P08050
Human: 2697, Mouse: 14609, Rat: 24392