CysLTR1 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | CysLTR1 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | CYSLTR1 |
| Recommended applications | ELISA, IF, IHC-p, WB |
| Reactivity | Human, Monkey |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CLTR1. AA range:131-180 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10964 |
Additional information
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CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. The cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
CYSLTR1, CYSLT1, Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81
Human: Q9Y271, Mouse: Q99JA4
Human: 10800