Cytokeratin 8 Monoclonal Antibody

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Product information

Price

€240, €410

Size

50 µl/µg | 100 µl/µg

Short name

Keratin type II cytoskeletal 8

Host

Mouse

Isotype

IgG

Target protein

KRT8

Reactivity

Human

Immunogen

Purified recombinant fragment of human Cytokeratin 8 (aa391-483) expressed in E. Coli.

Purification

Affinity purification

Formulation

Ascitic fluid containing 0.03% sodium azide;0.5% BSA; 50%glycerol.

Storage

-20°C for 1 year

Product code

MB-AM10337

Additional information

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8
Human: P05787, Mouse: P11679
Human: 3856