DACA-1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

DACA-1 Antibody

Host

Rabbit

Isotype

IgG

Target protein

YTHDF1

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human YTHDF1. AA range:1-50

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP10930

Additional information

The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. YTHDF2, also designated High-glucose-regulated protein 8, CLL-associated antigen KW-14 or Renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain. YTHDF3 is a 585 amino acid protein that also contains one YTH domain. The gene encoding YTHDF1 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
YTHDF1, C20orf21, YTH domain family protein 1, Dermatomyositis associated with cancer putative autoantigen 1, DACA-1
Human: Q9BYJ9, Mouse: P59326
Human: 54915, Mouse: 228994