Defensin Alpha4 Polyclonal Antibody
Prices are excluding VAT and shipping costs
Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | Defensin alpha4 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | DEFA4 |
| Recommended applications | ELISA, IHC-p |
| Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Defensin alpha4. AA range:27-76 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10897 |
Additional information
Prev
Next
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. Neutrophil defensin 4 encoded by DEFA4, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.
DEFA4, DEF4, Neutrophil defensin 4, Defensin, alpha 4, HNP-4, HP-4
Human: P12838
Human: 1669