DMBT1 Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

Deleted in malignant brain tumors 1 protein

Host

Rabbit

Isotype

IgG

Target protein

DMBT1

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human protein

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP12862

Additional information

Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Deleted in malignant brain tumors 1 protein ,Glycoprotein 340,Gp-340,Hensin,Salivary agglutinin,SAG,Surfactant pulmonary-associated D-binding protein
Human: Q9UGM3, Mouse: Q60997, Rat: Q8CIZ5
Human: 1755