Product information
Price | €175, €275, €395 |
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Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | DMGDH Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | DMGDH |
Recommended applications | ELISA, IHC-p, WB |
Reactivity | Human |
Immunogen | The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10869 |
Additional information
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DMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme (dimethylglycine dehydrogenase) is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH
Human: Q9UI17, Mouse: Q9DBT9
Human: 29958