DR3 Polyclonal Antibody
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Product information
| Price | €175, €275, €395 |
|---|---|
| Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
| Short name | DR3 Antibody |
| Host | Rabbit |
| Isotype | IgG |
| Target protein | TNFRSF25 |
| Recommended applications | ELISA, IHC-p, WB |
| Reactivity | Human |
| Immunogen | Synthesized peptide derived from DR3 . at AA range: 230-310 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Product code | MB-AP10838 |
Additional information
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Tumor necrosis factor receptor superfamily member 25 encoded by TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3, Apoptosis-mediating recep
Human: Q93038
Human: 8718