EFP Polyclonal Antibody

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Product information

Price

€175, €275, €395

Size

20 µl/µg | 50 µl/µg | 100 µl/µg

Short name

EFP Antibody

Host

Rabbit

Isotype

IgG

Target protein

TRIM25

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human ZNF147. AA range:201-250

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Product code

MB-AP10796

Additional information

The protein encoded by TRIM25 (tripartite motif containing 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of TRIM25 is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
TRIM25, EFP, RNF147, ZNF147, E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme T
Human: Q14258, Mouse: Q61510
Human: 7706