Product information
Price | €175, €275, €395 |
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Size | 20 µl/µg | 50 µl/µg | 100 µl/µg |
Short name | ERAB Antibody |
Host | Rabbit |
Isotype | IgG |
Target protein | HSD17B10 |
Recommended applications | ELISA, IHC-p, WB |
Reactivity | Human, Monkey, Mouse, Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human ERAB. AA range:111-160 |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Formulation | Liquid in PBS containing 50% glycerol; 0.5% BSA and 0.02% sodium azide. |
Storage | -20°C for 1 year |
Product code | MB-AP10720 |
Additional information
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HSD17B10 encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
HSD17B10, ERAB, HADH2, MRPP2, SCHAD, XH98G2, 3-hydroxyacyl-CoA dehydrogenase type-2, 17-beta-hydroxysteroid dehydrogenase 10, 17-beta-HSD 10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl
Human: Q99714, Mouse: O08756, Rat: O70351
Human: 3028, Rat: 63864